Spider-man 3 cheat: Defeating Venomto Defeat Venom In The Grand...
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Dfeeating Venom
To defeat Venom in the Grand Finale mission, hold LB then run and hit the boxes to drive him crazy. By holding LB while doing this, you will have more time to run whlie your opponent is in slow-motion.
The final button combination to defeat Venom is Up, A, Left, A(2), B, LB, X, LB, Y, RT.